经过评估，专家小组认为该添加剂对目标物种、消费者和环境是安全的。由于缺乏数据，研究小组无法就该添加剂对皮肤或眼睛产生刺激的可能性得出结论。评估中的添加剂被认为是非反刍动物物种氨基酸L-异亮氨酸的有效来源。为了使补充的L-异亮氨酸对反刍动物和非反刍动物同样有效，需要防止其在瘤胃中降解。部分原文报道如下：

 

　　Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of the feed additive consisting of l-isoleucine produced by fermentation with Corynebacterium glutamicum CGMCC 32505 as a nutritional additive in feed or water for drinking for all animal species and categories. The production strain is genetically modified. None of the genetic modifications raised a safety concern. Viable cells or DNA of the production strain were not detected in the final product. The use of l-isoleucine produced with C. glutamicum CGMCC 32505 in feed was considered safe for the target species when supplemented in appropriate amounts to the diet according to the nutritional needs. The FEEDAP Panel had concerns on the use of amino acids in water for drinking. The use of l-isoleucine (≥ 98.0%) produced with C. glutamicum CGMCC 32505 in animal nutrition was considered safe for the consumers and the environment. Regarding the safety for the user, owing to the lack of data, the FEEDAP Panel cannot conclude on the potential of the additive to be irritant to skin and/or eyes and to be a potential skin sensitiser. The additive was regarded as an effective source of the amino acid l-isoleucine for all non-ruminant species. To be as efficacious in ruminants as in non-ruminants, it should be protected from ruminal degradation.

 

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