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欧盟重新评估非转基因黑曲霉菌株CTS 2093生产的过氧化氢酶的安全性

时间:2026-06-08

   食品伙伴网讯  2026年6月5日,欧盟食品安全局就一种食品酶过氧化氢酶(catalase)的安全性评价发布意见。
 
  据了解,这种食品酶是由非转基因黑曲霉菌株CTS 2093生产的。根据提供的新数据和以前的评估,专家小组得出结论,这种食品酶在预期使用条件下不会引起安全问题。部分原文报道如下:
 
  The food enzyme catalase (hydrogen-peroxide:hydrogen-peroxide oxidoreductase; EC 1.11.1.6) is produced with the non-genetically modified Aspergillus niger strain CTS2093 by Shin Nihon Chemical Co., Ltd. In a previous evaluation, the Panel could not exclude safety concerns due to an insufficient margin of exposure (MoE). As a follow-up, the applicant updated the intended uses, conducted an in vitro micronucleus test using a new food enzyme batch and updated the homology search for allergenicity. In the present evaluation, the dietary exposure was calculated to be up to 0.032 mg total organic solids (TOS)/kg body weight (bw) per day in European populations. When combined with the no observed adverse effect level previously reported (56 mg TOS/kg bw per day), the Panel derived an MoE of at least 1750. based on the new data, the revised MoE and the previous evaluation, the Panel concluded that this food enzyme does not give rise to safety concerns under the intended conditions of use.
 
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