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欧盟评估谷氨酸棒杆菌CGMCC 23982生产的L-赖氨酸盐酸盐作为所有动物饲料添加剂的安全性和有效性

时间:2026-04-03

   食品伙伴网讯  2026年4月1日,据欧盟食品安全局EFSA)消息,应欧盟委员会要求,欧盟动物饲料添加剂和产品(FEEDAP)研究小组就谷氨酸棒杆菌CGMCC 23982发酵生产的L-赖氨酸盐酸盐(l-lysine monohydrochloride)作为所有动物饲料添加剂的安全性和有效性发表科学意见。
 
  经过评估,专家小组认为该添加剂对目标物种、消费者和环境是安全的。评估中的添加剂被认为是所有非反刍动物物种氨基酸L-赖氨酸的有效来源。为了使补充的L-赖氨酸对反刍动物和非反刍动物同样有效,需要防止其在瘤胃中降解。部分原文报道如下:
 
  Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of l-lysine monohydrochloride produced with a non-genetically modified strain of Corynebacterium glutamicum (CGMCC 23982) as a nutritional additive to be used in feed and water for drinking for all animal species and categories. The production strain C. glutamicum CGMCC 23982 does not raise safety concerns. The use of l-lysine monohydrochloride in feed produced with C. glutamicum CGMCC 23982 in feed is safe for the target species when supplemented in appropriate amounts to the diet according to the nutritional needs of the target species. The FEEDAP Panel has concerns on the use of l-lysine monohydrochloride in water for drinking. The use of l-lysine monohydrochloride produced by fermentation with C. glutamicum CGMCC 23982 in animal nutrition is considered safe for the consumers and for the environment. Regarding user safety, l-lysine monohydrochloride produced with C. glutamicum CGMCC 23982 is irritant to the skin and eyes and is considered a respiratory irritant. Exposure by any route is considered a risk. The feed additive consisting of l-lysine monohydrochloride produced by fermentation with C. glutamicum CGMCC 23982 is regarded as an effective source of the amino acid l-lysine for all non-ruminant species. In order to be as efficacious in ruminants as in non-ruminants, it should be protected from ruminal degradation.
 
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