经过评估,专家小组认为该添加剂对目标物种、消费者和环境是安全的。评估中的添加剂被认为是所有非反刍动物物种氨基酸L-缬氨酸的有效来源。为了使补充的L-缬氨酸对反刍动物和非反刍动物同样有效,需要防止其在瘤胃中降解。部分原文报道如下:
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of L-valine produced by fermentation using the non-genetically modified strain of Corynebacterium glutamicum KCCM 80366 as a nutritional feed additive for all animal species and categories. In the manufacturing process used to obtain the product under assessment, the cells from the production strain are inactivated but not removed from the final product. The FEEDAP Panel concluded that the production strain follows the qualified presumption of safety (QPS) approach to safety assessment, as the strain does not harbour any gene of concern and no viable cells of the strain were detected in the final product. The use of L-valine produced using C. glutamicum KCCM 80366 in animal nutrition is considered safe for all animal species, the consumers of products from animals receiving the additive, and the environment. Regarding the safety for the users, the additive is not considered irritant to skin but was considered a potential skin and respiratory sensitiser. The FEEDAP Panel could not conclude on the potential of the additive to be irritant to eyes. Any exposure to the additive is a risk. The additive was regarded as an effective source of the amino acid L-valine for all non-ruminant species. To be as efficacious in ruminants as in non-ruminants, it should be protected from ruminal degradation.
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